Description
Background: After 3 years of the covid-19 epidemic and 4 epidemic peaks, this study aimed to identify factors linked to anti-covid-19 immunity in a low prevalence area.
Methods: As part of a national seroprevalence survey conducted in 2023, specific information from the Mono department was collected. Sociodemographic and clinical data, medical history, history related to covid-19, vaccination status and vaccine-related information were collected from 151 subjects. On blood samples taken in a hospital setting, analyses focused on serological status with the detection of anti-NCP IgG, anti-Spike IgG antibodies and total antibody titration. A logistic regression model was constructed.
Results: Slightly more than half of the population had overall immunity, 51.65%. The mean age (SD) was 31.96 (17.03) years and the sex ratio M/F: 0.8. Nearly 40% resided in urban areas and 27.61% were not in school. Less than 10% reported having already contracted covid-19 at least once and vaccination coverage was 29.53%. Subjects aged [20-40 years] were the most seroprevalent 38.74%. Factors associated with a higher probability of having overall immunity against covid-19 were age (OR=2.04 [1.24-3.75]), female sex (OR=4.02 [1.74-5.28]), and vaccination status (OR=2.01 [1.64-3.89]). Conversely, living in a rural or semi-rural environment reduced the probability of having immunity (OR=0.47 [0.36-0.81]).
Conclusion: This study shows that the COVID-19 virus has circulated more strongly in urban areas, among young people and women. The vaccination campaign has also demonstrated its benefits.
Key-words: overall Covid-19 immunity – young subjects – female sex – vaccination
| Section | Recherche originale |
|---|---|
| Mot-clé 1 | overall Covid-19 immunity |
| Mot-clé 2 | young subjects |
| Mot-clé 3 | female sex |
| Mot-clé 4 | vaccination |
