9–11 sept. 2025
Palais des congrès de Cotonou
Fuseau horaire Africa/Porto-Novo

Post-covid-19 sequelae in Guinea: A prospective cohort study

P04_173
Non programmé
10m
Palais des congrès de Cotonou

Palais des congrès de Cotonou

Boulevard de la Marina, Cotonou
Communication affichée Santé Publique en milieu hospitalier

Orateur

Kadio Jean-Jacques Olivier KADIO (Centre de Recherche et de Formation en Infectiologie de Guinée (CERFIG))

Description

Background
Understanding post-covid-19 sequelae even after the end of the pandemic requires attention to the development of relevant integrated care pathways. Few studies have been conducted in sub-Saharan Africa in the post-omicron period. Our study was focusing on post-COVID-19 sequelae among individuals who recovered during the Omicron wave.

Methods

This was a dynamic prospective cohort study conducted between May 2023 and October 2024. The study included 65 participants aged 18 and above, initially diagnosed with SARS-CoV-2 during the 2022-2023 Omicron wave and confirmed negative by PCR. Participants were recruited from the Nongo Epidemic Treatment Center and the CERFIG laboratory database in Guinea. Data were collected during three visits: at inclusion, and at 6 and 12 months post-inclusion.

Results

During the acute phase of COVID-19, 80% of participants reported symptoms, with the most common being headaches (62%), fever (51%), fatigue (49%), cough (32%), and myalgias (22%). At the 6-month and 12-month follow-ups, 18% of participants exhibited persistent clinical sequelae. Mental health assessments revealed a decline in sleep quality, with 70.5% and 67.5% of participants reporting poor sleep at 6 and 12 months, respectively. Depression scores decreased over time, with 20% of participants showing depressive symptoms at inclusion, 17.7% at 6 months, and 7.5% at 12 months. Neurological impairments were prevalent, affecting 80% of participants at inclusion, 71.1% at 6 months, and 77.5% at 12 months.

Conclusion

The study highlights the significant persistence of post-COVID-19 clinical and mental health sequelae, particularly sleep disturbances and neurological issues, underscoring the need for continued support and intervention strategies for affected individuals in African regions particularly among patients in Guinea.

Keys words: Post-covid-19 sequelae, Omicron, Guinea

Section Recherche originale
Mot-clé 1 Post-covid-19 sequelae,
Mot-clé 2 Omicron
Mot-clé 3 Guinea

Author

Kadio Jean-Jacques Olivier KADIO (Centre de Recherche et de Formation en Infectiologie de Guinée (CERFIG))

Co-auteurs

Prof. Abdoulaye TOURE (Centre de Recherche et de Formation en Infectiologie de Guinée (CERFIG), Université Gamal Abdel Nasser de Conakry) Dr Ahidjo AYOUBA (Institut de Recherche pour le Développement, TRANSVIHMI, Université de Montpellier, France) Dr Alain MAKINSON (Institut de Recherche pour le Développement, TRANSVIHMI, Université de Montpellier, France) Prof. Alpha Kabinet KEITA (Centre de Recherche et de Formation en Infectiologie de Guinée (CERFIG)) Dr Charlotte BOULLE (Institut de Recherche pour le Développement, TRANSVIHMI, Université de Montpellier, France) Dr Christian LIENHARDT (Institut de Recherche pour le Développement, TRANSVIHMI, Université de Montpellier, France) Prof. Eric DELAPORTE (Institut de Recherche pour le Développement, TRANSVIHMI, Université de Montpellier, France) Prof. Mamadou Saliou SOW (Centre de Recherche et de Formation en Infectiologie de Guinée (CERFIG), Université Gamal Abdel Nasser de Conakry) Dr Mariama Sall DIALLO (Centre de Recherche et de Formation en Infectiologie de Guinée (CERFIG)) Dr Maryline BONNET (Institut de Recherche pour le Développement, TRANSVIHMI, Université de Montpellier, France)

Documents de présentation

Actes