Description
Background: In Benin, a vaccination strategy has been implemented to protect the population, particularly against severe forms of COVID-19. The objectives of this study were to investigate the impact of vaccination on the risk of respiratory distress in these patients.
Methods: A prospective case-control study including 612 patients with SARI was conducted over a six-month period in 2023 in four hospitals in Benin. The diagnosis of SARS-CoV-2 infection was confirmed by PCR testing. Sociodemographic, clinical, and environmental data, medical history, COVID-19 history, vaccination status, and vaccine-related information were collected. A logistic regression model was performed.
Results: The mean age (SD) was 57.12 (6.36) years; the majority were female, with 61.44%; 38.72% had a secondary education; and 50.01% lived in urban areas. 50.98% had comorbidities and 73.86% had respiratory distress. Vaccination coverage was 19.60%, representing 120 subjects. Vaccination status reduced the risk of developing respiratory distress (OR=0.69 [0.44-0.90]); conversely, age (OR=3.21 [1.87-4.16]) and the presence of comorbidities (OR=2.05 [1.25-3.87]) were associated with a higher risk of respiratory distress.
Conclusion: This study showed a positive effect of vaccination on the risk of developing respiratory distress, highlighting that the vaccination strategy was a good intervention in the fight against COVID-19, especially in patients with severe cases.
Key-words: COVID-19 – SARI – Respiratory Distress – Vaccination
| Section | Recherche originale |
|---|---|
| Mot-clé 1 | COVID-19 |
| Mot-clé 2 | SARI |
| Mot-clé 3 | Respiratory Distress |
| Mot-clé 4 | vaccination |
