Description
Background: COVID-19 vaccines were introduced to ensure protection of the population, especially against severe forms. The objective of this study was to investigate the effect of vaccination on the duration of hospitalization in subjects with severe acute respiratory infection.
Methods: Sociodemographic, clinical, and environmental data, medical history, COVID-19 history, vaccination status, and vaccine-related information were collected from 612 subjects with SARI during a prospective case-control study conducted in 2023 in four hospitals in Benin. The diagnosis of SARS-CoV-2 infection was confirmed by PCR testing. A linear regression model was performed.
Results: Vaccination coverage was 19.60%, representing 120 subjects. The mean age (SD) was 57.12 (6.36) years; the majority were female, with 61.44%; 38.72% had a secondary education; 50.01% lived in an urban area; and 50.98% had comorbidities. The mean length of hospital stay was 18.95 days (6.51). Vaccination status reduced hospital stay (coefficient = -5.50; p = 0.002). Conversely, age (coefficient = 6.85; p = 0.003) and the presence of comorbidities (coefficient = 4.17; p = 0.01) were associated with an increased length of hospital stay.
Conclusion: This study showed that being vaccinated reduced hospital stay. Vaccination was a good intervention in the fight against COVID-19, especially in patients with severe disease.
Key-words: Covid-19 – IRAS – Length of hospitalization – Vaccination.
| Section | Recherche originale |
|---|---|
| Mot-clé 1 | COVID-19 |
| Mot-clé 2 | SARI |
| Mot-clé 3 | Length of hospitalization |
| Mot-clé 4 | vaccination |
